Serena Williams became the most successful woman in Grand Slam history after registering her 307th win in a major, beating the women's Open era record that Martina Navratilova previously held. Top seed Williams's 6-2 6-1 win against Johanna Larsson also put her level with Roger Federer for most match wins in a major in the Open era. The way the 34-year-old American is playing, she is more than likely to break Federer's record in her next match.

Nick Kyrgios's tearful exit

Big things were expected from the Nick Kyrgios, but a hip injury forced him to retire from his match against Ukraine's Illya Marchenko. Kyrgios was trailing 4-6 6-4 6-1 in the match before pulling out. The 21-year-old said that his hip was troubling him from the start of the tournament. "My physio has been helping me all week. I’ve been trying to fix it all week. But it’s the whole year leading up to it with the whole schedule. I got to take more time and be more diligent with the gym and everything so this doesn’t happen to me," he said.

Murray, Wawrinka and Nishikori all survive scares

Andy Murray's hard-fought 7-6 (4), 5-7, 6-2, 6-3 win over Paolo Lorenzi meant that for the first time in the Open era, there will be two British men in the round of 16 stage. Lorenzi, seeded 40th, took off from where he left in his second round win against Gilles Simon. It was only during the last two sets that the Olympic gold medallist came into his own as his opponent ran out of steam. Murray will now face Grigor 'Baby Federer' Dimitrov in the round of 16.

Stanislas Wawrinka was a solitary point away from being another big casualty at the US Open against British No. 2 Daniel Evans, who did everything but seal the tie. Wawrinka was staring a defeat, with Evans leading 6-5 in the fourth set. From match point, the third-seeded Wawrinka fought his way back in the game despite suffering an ankle injury during the game to win 4-6, 6-3, 6-7(6), 7-6(8), 6-2.

Like Evans, Nicolas Mahut also had the chance to register a major upset, but the 2014 finalist Kei Nishikori rose from the brink to win the match 4-6, 6-1, 6-2, 6-2.

Del Potro's fairytale comeback 

The injury-plagued Juan Martin del Potro had made a rousing comeback in the Rio Olympics, going all the way to the summit clash before losing to Murray, but clearly that was simply a good beginning. The Argentinian thrashed David Ferrer 7-6 (7) 6-2 6-3 to register a place in the round of 16. His next opponent(s) better beware as there were signs of his blistering forehand slowly getting back to full cry.

Bopanna flags Indian hopes

The mixed doubles pair of Leander Paes and Martina Hingis suffered a second-round defeat at the hands of USA's Coco Vandeweghe and Rajeev Ram. Meanwhile, Rohan Bopanna and his Canadian partner Gabriela Dabrowski are through to the quarter-finals after beating Andrea Hlavackova and Lukasz Kubot.