Defending champion Novak Djokovic and nine-time winner Rafael Nadal were drawn to face each other in a blockbuster French Open semi-final on Friday.

Nadal is chasing a 10th title at Roland Garros while second seed Djokovic, working with new coach Andre Agassi, is looking to defend the only major he still holds.

World No. 1 Andy Murray is seeded to face 2015 champion Stanislas Wawrinka in the last four. Murray starts against Russia’s Andrey Kuznetsov while Djokovic tackles Spanish clay courter Marcel Granollers while Nadal meets combustible Frenchman Benoit Paire.

If the seedings work out, 2016 runner-up Murray, who is reportedly suffering from an illness, would face Japan’s Kei Nishikori in the last eight.

The other quarter-finals would see Wawrinka meet 2014 US Open champion Marin Cilic, Nadal would meet Canada’s Milos Raonic while Djokovic could take on Dominic Thiem.

Djokovic demolished highly-regarded Austrian Thiem for the loss of just one game in the Rome Masters semi-finals last week. The 30-year-old Nadal has already reached the magical 10 titles number this year at the claycourt events in Monte Carlo and Barcelona.

Nadal has already reached the magical 10 titles number this year at the claycourt events in Monte Carlo and Barcelona. For good measure, he also won Madrid for a fifth time, ending a seven-match losing streak, stretching back over two years against Djokovic in the process.

Nadal boasts a sensational career record at Roland Garros – 72 wins and just two defeats, to Djokovic in 2015 and an injury-affected shock loss to Robin Soderling in 2009.

Among the other games to watch out for, Zverev faces Spanish veteran Fernando Verdasco first up, Thiem tackles Bernard Tomic of Australia while fellow ‘NextGen’ star Nick Kyrgios faces Philipp Kohlschreiber of Germany.

Nishikori, yet to get past the quarter-finals in Paris, begins against 21-year-old Australian Thanasi Kokkinakis.

Women’s draw

In the women’s draw, top seed Angelique Kerber starts against experienced Russian Ekaterina Makarova in the first round.

Kerber is due to face defending champion Garbine Muguruza of Spain in the semi-finals. “I am super-excited to be here. I am preparing the best I can but there is no magic pattern,” said Muguruza who comes into the tournament having suffered a neck injury in Rome last week.

Muguruza has a tough opener against former champion Francesca Schiavone. Second seed Karolina Plisova was drawn to face 2014 runner-up Simona Halep in the semi-finals but will start against Zheng Saisai of China.

Halep has an ankle injury and described her chances of making Roland Garros as “50-50” earlier this week.

The women’s event is regarded as being wide open with Serena Williams, Maria Sharapova and Victoria Azarenka al absent.

If the seedings works out, Kerber will face former champion Svetlana Kuznetsova in the last eight with Muguruza against Dominika Cibulkova.

Elina Svitolina would face Halep, who she defeated in the Rome final, while Britain’s Johanna Konta would be Pliskova’s last-eight rival.

Petra Kvitova, who is recovering from a knife attack, has also been included in the draw at Roland Garros. She will start her comeback campaign against Julia Boserup in the first round.