Passionate and heartfelt declarations of love abound in the trailer of Life Itself, which was released by Amazon Studios on Tuesday. Written and directed by Dan Fogelman (who made the hit television series This is Us), the multi-generational love story is set among people living in New York and Spain, describing how their lives intertwine.

The trailer begins by highlighting the relationship between Will (Oscar Isaac) and Dylan (Olivia Wilde), and goes on to depict other characters. The high-powered cast includes Annette Bening, Samuel L Jackson, Antonio Banderas, Mandy Patinkin and Laia Costa.

Life Itself will be released in the United States of America on September 21.

Life Itself.