World no 1 Carlos Alcaraz edged closer to a US Open rematch with Italy’s Jannik Sinner on Thursday as Grand Slam winners Aryna Sabalenka and Marketa Vondrousova booked their places in the third round.

Defending champion Alcaraz eased into a last 32 meeting with Britain’s Dan Evans after dispatching South Africa’s Lloyd Harris 6-3, 6-1, 7-6 (4) in 2hr 28min at the Arthur Ashe Stadium.

It means Alcaraz is just two wins away from a potential quarter-final collision with Italian sixth seed Sinner, who continued his serene progress through the draw with a 6-4, 6-2, 6-4 defeat of compatriot Lorenzo Sonego.

Last year, Alcaraz and Sinner produced an epic five-set quarter-final classic that was not completed until 2:50am local time – the latest ever finish in US Open history.

After their performances on Thursday, few would bet against a repeat of last year’s heavyweight slugfest in this year’s quarter-finals.

“I think I played a great match from the beginning to the last ball,” Alcaraz said after his defeat of Harris.

“To be able to win in straight sets is really important to me in the first rounds,” added Alcaraz, who is bidding to become the first man to defend the US Open since 2008, when Roger Federer hoisted the trophy for a fifth straight year.

The 22-year-old Sinner meanwhile looks to be firing on all cylinders on the evidence of his second round performance.

The Italian conceded just 10 points on serve without giving Sonego a single break point throughout the 2hr 5min encounter.

Sinner will play 2016 US Open champion Stan Wawrinka in the third round on Saturday. Wawrinka, 38, rolled back the years to beat Argentine No 30 seed Tomas Martin Etcheverry 7-6 (6), 6-7 (7), 6-3, 6-2.

Germany’s 12th seed Alexander Zverev is also potentially lurking in Sinner’s path before a quarter-final with Alcaraz.

Zverev booked his place in the third round with a 7-6 (1), 3-6, 6-4, 6-3 defeat of compatriot Daniel Altmaier.

Champions advance

Elsewhere on Thursday, Britain’s 2012 US Open champion Andy Murray slumped to a 6-3, 6-4, 6-1 loss to Bulgarian 19th seed Grigor Dimitrov.

Former world No 3 Dimitrov, who saved three match points in the opening round, meets 2020 runner-up Zverev in the last 32.

“It’s obviously disappointing, to not play how you would like,” said Murray, who hit 45 unforced errors and just 16 winners, following his loss to Dimitrov.

While Murray tumbled out, fellow Britons Jack Draper and Katie Boulter both advanced to the third round in contrasting fashion in their second round matches.

Draper upset Polish 17th seed Hubert Hurkacz 6-2, 6-4, 7-5 to set up a third round meeting with American wild card Michael Mmoh, who defeated John Isner 3-6, 4-6, 7-6 (3), 6-4, 7-6 (7) in what was the final game of the big-serving veteran’s career.

Boulter came from behind to beat China’s Wang Yafan 5-7, 6-1, 6-4.

But another Briton, Jodie Burrage, saw her tournament come to an end after a one-sided defeat to second seed Sabalenka of Belarus, the reigning Australian Open champion. Sabalenka prevailed 6-3, 6-2 in 1hr 14min.

Sabalenka, 25, has reached the semi-finals or better at the past four Grand Slams and can replace Iga Swiatek as world No 1 if she matches the Pole’s result in New York.

“I’m not really focused on that, but it’s going to mean a lot to me,” said Sabalenka. “It’s one of my goals, one of my dreams and I’ll do my best to reach my dream.”

Another of 2023’s Grand Slam winners, Wimbledon champion Vondrousova of the Czech Republic, could meet Sabalenka in the semi-finals.

Vondrousova, who made history by becoming the first unseeded woman to win Wimbledon in July, had too much firepower for Italy’s Martina Trevisan, winning 6-2, 6-2 in 1hr 20min.

The ninth seed said afterwards she is adjusting to being the hunted rather than the hunter in the wake of her unexpected Wimbledon triumph.

“It’s a tough position,” Vondrousova said. “I feel like everybody wants to beat me. I’m just happy to be here and play good tennis.”

Meanwhile Tunisia’s fifth seed Ons Jabeur, runner-up at last year’s US Open final and beaten by Vondrousova in the Wimbledon final in July, was put through the grinder in a 7-6 (9/7), 4-6, 6-3 defeat of Czech teenager Linda Noskova.

Results from day four of the US Open at USTA Billie Jean King Tennis Center on Thursday (x denotes seed):

Men’s singles second round

Carlos Alcaraz (ESP x1) bt Lloyd Harris (RSA) 6-3, 6-1, 7-6 (7/4)

Dan Evans (GBR x26) bt Botic van de Zandschulp (NED) 1-6, 6-1, 6-3, 6-3

Matteo Arnaldi (ITA) bt Arthur Fils (FRA) 3-6, 7-5, 7-6 (7/5), 5-7, 6-4

Cameron Norrie (GBR x16) bt Hsu Yu-hsiou (TPE) 7-5, 6-4, 6-4

Alexander Zverev (GER x12) bt Daniel Altmaier (GER) 7-6 (7/1), 3-6, 6-4, 6-3

Grigor Dimitrov (BUL x19) bt Andy Murray (GBR) 6-3, 6-4, 6-1

Stan Wawrinka (SUI) bt Tomas Martin Etcheverry (ARG x30) 7-6 (8/6), 6-7 (7/9), 6-3, 6-2

Jannik Sinner (ITA x6) bt Lorenzo Sonego (ITA) 6-4, 6-2, 6-4

Sebastian Baez (ARG) bt Felipe Meligeni Alves (BRA) 6-7 (7/9), 6-4, 6-4 - retired

Nicolas Jarry (CHI x23) bt Alex Michelsen (USA) 4-6, 6-3, 6-3, 6-3

Alex de Minaur (AUS x13) bt Wu Yibing (CHN) 6-1, 6-2, 6-1

Michael Mmoh (USA) bt John Isner (USA) 3-6, 4-6, 7-6 (7/3), 6-4, 7-6 (10/7)

Jack Draper (GBR) bt Hubert Hurkacz (POL x17) 6-2, 6-4, 7-5

Arthur Rinderknech (FRA) bt Matteo Berrettini (ITA) 6-4, 5-3 - retired

Andrey Rublev (RUS x8) bt Gael Monfils (FRA) 6-4, 6-3, 3-6, 6-1

Women’s singles second round

Katie Boulter (GBR) bt Wang Yafan (CHN) 5-7, 6-1, 6-4

Peyton Stearns (USA) bt Clara Tauson (DEN) 6-3, 6-0

Ekaterina Alexandrova (RUS x22) bt Lesia Tsurenko (UKR) 6-1, 6-3

Marketa Vondrousova (CZE x9) bt Martina Trevisan (ITA) 6-2, 6-2

Liudmila Samsonova (RUS x14) bt Tamara Korpatsch (GER) 6-3, 6-3

Madison Keys (USA x17) bt Yanina Wickmayer (BEL) 6-1, 6-2

Elina Svitolina (UKR x26) bt Anastasia Pavlyuchenkova (RUS) 5-7, 6-4, 6-4

Ons Jabeur (TUN x5) bt Linda Noskova (CZE) 7-6 (9/7), 4-6, 6-3

Marie Bouzkova (CZE x31) bt Petra Martic (CRO) 6-1, 6-2

Zheng Qinwen (CHN x23) bt Kaia Kanepi (EST) 6-2, 3-6, 6-2

Lucia Bronzetti (ITA) bt Eva Lys (GER) 6-3, 6-2

Daria Kasatkina (RUS x13) bt Sofia Kenin (USA) 2-6, 6-4, 6-4

Clara Burel (FRA) bt Karolina Pliskova (CZE x25) 6-4, 6-2

Aryna Sabalenka (BLR x2) bt Jodie Burrage (GBR) 6-3, 6-2